Folic acid during pregnancy is a necessary substance for the body of a woman and tooling the fetus.
The deficiency of folate compounds or vitamin B9 is dangerous and leads to a change in blood composition in the future mother and child, disorders in the development of the placenta. The consequence is the birth of premature children or children with pathologies in development.
Meaning for the body
Folic acid is in food products:
- broccoli;
- green pea;
- carrot;
- bananas;
- citrus;
- sheet greens;
- yeast;
- bread products, etc.
For the receipt of the required amount of B9, a balanced diet is required. But even in this case, the development of vitamin deficiency is possible.
The reason is in the rapid destruction of folic acid when storing products. Moreover, the need of a pregnant woman in vitamin increases significantly.
Other causes of folic acid deficiency:
- small receipt with food;
- genetic diseases (in the body there are no enzymes for the assimilation and processing of folates);
- chronic bowel or stomach diseases (normal suction of the substance violates);
- hobbating with alcohol;
- the use of certain drugs - sulfonamides, oral contraception, anticonvulsant, antacids, anti-tuberculosis means.
Folic acid during pregnancy
Lack of vitamin B9 - Beach among pregnant women today. If the future mother has constant weakness, increased fatigue, anemia, dizziness and headaches, irritability - possibly the reason exactly in the deficiency of folic acid.
The value of vitamin in the body is huge to produce proteins and nucleic acids. It is necessary for the regeneration of cells and tissues, maintaining in the norm of all organs, preventing the transformation of cells into cancer.
An even large role of folic acid during pregnancy. It provides normal growth and development of the fetus.
Sufficient folate content is important in 1 trimester. These months are laid by all organs and systems of the embryo, and the most important thing is its nervous tissue and placenta vessels.
What is dangerous deficit?
The main danger of vitamin B9 deficiency during pregnancy is insufficient development in the neural tube embryo.
This leads to such malformations:
- failure to pregnancy, that is, the death of the fetus is intrauterine;
- hydrocephalus, it is the same or water brain;
- anencephalia, that is, the embryo is completely absent brain;
- spinal cleft;
- brain hernia;
- impaired mental function;
- physical underdevelopment.
Great value of folic acid for the vascular system in the uterus. Consequences of lack of substance:
- premature placental detachment;
- spontaneous interruption of pregnancy.
The deficit of folate on the well-being of a pregnant woman. Manifestations are:
- toxicosis on early timing;
- rapid fatigue;
- weakness;
- decline in appetite;
- digestion disorders;
- headache and dizziness;
- cramps in the legs.
For this reason, doctors recommend drinking folic acid at the stage of pregnancy planning. In fact, women often learn about conception on a period of 5-6 weeks, namely, during this period, the embryo is particularly acutely susceptible to the deficiency of vitamin.
How to use?
Folic acid is produced in the form of tablets in its pure form or in a complex with cyancobalamin (vitamin B12) or ascorbic acid. Vitamins and biological supplements with B9 are also produced.
Tablets drink, not chewing and drinking with simple water. Reception regardless of food.
When to start?
Begin to drink folic acid better before conception. This will warn possible pathology.
WHO - the World Health Organization recommends that all women in the presence of folic acid and iron preparations. Dosage appoints a doctor leading pregnancy. It is necessarily taken into account the history of women, the presence of any chronic diseases.
To what period of drinking?
Folic acid during pregnancy is especially important in the first trimester, that is, with conception and until the term of 12 weeks.
Then you can refuse to refuse the drug under the condition that there is no manifestation of its insufficiency. In some cases, the woman is prescribed vitamin and further - in 2 and 3 trimesters.
It is desirable to start drinking folic acid when planning pregnancy, then before childbirth and completion of breastfeeding.
The dosage varies depending on the timing:
- The planning period is 400 μg daily.
- The first trimester of pregnancy - 600 - 800 μg.
- From the 13th week and before the end of pregnancy - 800 μg per day.
- In the period of breastfeeding - 400 - 600 μg per day.
If there is a need, the day dose of the gynecologist can increase:
- With miscarriages, fetal fetus, the birth of children with defects - 4 mg per day.
- In diabetes mellitus or epilepsy, a woman is 1 mg.
- When receiving certain drugs - 800 μg - 4 mg per day (anticonvulsant, sulfonamides, alcohol-based medicines, anti-tuberculosis, etc.).
Preparations
Folic acid produce both in pure form and in the form of drugs:
- Folic acid tablets. Contains 1 mg vitamin B9. For prevention, the recommended dosage is 1 tablet per day.
- Folio. Contains 400 μg of folates in combination with 200 μg iodine. Reception prevents the lack of B9 and iodine in the body of a pregnant woman.
- Flavin. The content of the active substance in the tablet is high - 5 mg. Therefore, it is not used for prophylaxis, but for the treatment of deficit.
- Gendevit. Polevitamin in the form of dragee. In one - 300 μg of folic acid.
- Combivit mom. Poly vitamin complex. In one capsule - 400 μg of vitamin.
Contraindications
Folic acid during pregnancy is contraindicated for receiving in the following cases:
- allergic reaction or individual intolerance of folic acid;
- oncological diseases in close relatives;
- vitamin B12 deficiency;
- chronic pyelonephritis;
- bronchial asthma.
On video about folic acid
Consequences overdose
Overdose vitamin B9 during pregnancy is difficult to achieve, as this water-soluble substance. His assimilation by the body occurs only in the right amount, and the excess is derived by the kidneys.
However, the symptoms of overdose of folic acid are as follows:
- unfortunate irritability;
- disorders of the digestive system - nausea and vomiting, meteorism, diarrhea, lack of appetite;
- insomnia;
- disruption of the kidney function.
The overdose of folic acid is spoken in the case of a daily dose in the body of a daily dose of more than 15 mg.
Folic acid during pregnancy - vitamin necessary to maintain the body of the future mother and the proper development of the fetus. The B9 deficiency leads to irreversible consequences in the form of defects at the embryo. To prevent complications, the reception of folic acid is advisable to start at the stage of pregnancy planning and continue up to 12 weeks, and even better before childbirth and ending breastfeeding.
Thank you
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general information
About benefit folic acid (Vitamin B 9) People have known for a long time, but only in the last 10 years, doctors have become actively promoted by prophylactic folic acid reception courses for pregnant women and suffering from iron deficiency.Folic acid takes part in the metabolism, in the production of DNA, plays an important role in the synthesis of immune blood cells, normalizes the function of the digestive tract. For pregnant women, folic acid is essential because it plays an important role in the development of the nervous tube of the fetus. At a normal level of vitamin in 9, the likelihood of malformations in the fetus is significantly reduced. In addition, it is necessary for the normal growth and development of the placenta.
History opening
In 1926, the microbiologist V. Efremov discovered in pregnant women a specific form of Malokrovia - Megaloblastic anemia. Then the vitigiousness has developed rapidly, many scientists conducted research in this area of \u200b\u200bknowledge. Most of all appeared on the food factor. Efremov accurately determined the presence of a certain anti-diamemine factor in the liver tissue - in patients who received food from the liver, significant improvements were observed.In 1932, the British Wils Doctor, who worked in India for many years, found that some pregnant women suffering from megaloblastic anemia did not have an improvement in the use of purified liver cell extract. However, these women were fully recovered after eating a crude extract. From here Wils concluded that when purified, some important factor caused by recovery was destroyed. This substance was soon allocated and received the name - the Wils factor. It was later called Vitamin M. In 1941, it was found that the leaves of spinach and parsley are rich in this substance - therefore it was renamed to folic acid (translated from the Latin Folium list).
Mechanism of action
Finding into the body, vitamin B 9 turns into tetrahydrofolate, which serves as a component of many enzymes, and also participates in a number of biochemical reactions, such as protein exchange. As a result, the organism is synthesized for the formation of amino acid proteins, epinephrine and some other factors. Also, Vitamin B 9 has an effect similar to estrogen - determines the correct development of the reproductive system of the woman.It is well known that the first and most important phase of dividing any cell is dividing the DNA molecule. It is in the process of replication DNA Vitamin B 9 takes an active part. In addition, it plays an important role in the process of RNA synthesis, amino acids, improves iron absorption. Therefore, the lack of folic acid is primarily dangerous for rapidly divided cells.
The mood also depends on the level of folic acid. It takes part in the metabolism of such neurotransmitters as serotonin and adrenaline, which have a significant impact on the work nervous system.
Folic acid stimulates appetite and takes part in the release of hydrochloric acid in the stomach.
Folic acid need
In the liver of a person, a certain amount of folacine is usually contained, which can prevent hypovitaminosis within 3-6 months. The organism of an adult needs 0.4 mg of folic acid per day, during pregnancy and during lactation - 0.4-0.6 mg, the child of the 1st year of life is 0.04-0.06 mg. In the normal state of the intestinal flora, Vitamin B 9 can be made endogeneously.Folic acid and pregnancy
Daily maintenance of a normal level of folic acid a few months before pregnancy helps to reduce the risk of congenital malformations of the fetus. Clinical studies have demonstrated that 80% of cases of malformations can be prevented if the woman starts to replenish the lack of vitamin 9 before pregnancy.In the Russian Federation it is assumed that the need for pregnant women without symptoms of the lack of this micronutrient is 0.4 mg per day. In the period of breastfeeding, the need is 0.6 mg per day.
During pregnancy, the body of a woman consumes much more folic acid than before pregnancy. Vitamin B is not postponed about the reserve, so it is important to get it daily from external sources. It is very important to maintain the necessary level of folic acid in the first trimester when the nervous system of the fetus develops.
The most important role of vitamin B 9 for the fetus is the development of the nervous tube. It also takes part in the update and mitosis of the cells of the mother's organism, in particular cells of the internal organs that must be constantly updated.
Already in the second week of pregnancy, the embryo begins to actively develop a brain. It is at this time that even a short vitamin deficit at 9 threatens serious, often irreparable consequences. Since this micronutrient is needed in the mitosis process, which is extremely important for rapidly divided and developing cells (to them, first of all, neurons and other cells of nervous tissue include, its lack, first of all, affects the developing nervous system.
Folic acid is involved in the production of basic blood cells (erythrocytes, leukocytes and platelets), which is important both for the body of the mother and for the fetus.
For the normal course of pregnancy, maintaining the health of women and the fetus, doctors are recommended to start receiving folic acid in the form of tablets for another 2-3 months before the planned pregnancy, and continue until childbirth. When using vitamin in 9, it is necessary to adhere to the doses recommended by the attending physician, since the excess of this micronutrient is also dangerous as its deficit.
Vitamin B 9 is the only micronutrient whose role during pregnancy does not even undertake opponents of synthetic vitamin preparations and general medicines. Therefore, even if you avoid any drugs during pregnancy, do not refuse the Vitamin Course of 9, at least for the purpose of prevention - it will save you and your child from a variety of unjustified risks. Although sometimes you should compare the dosage appointed by the doctor with the needs of the body in folic acid.
Folic acid deficiency and its consequences
With thermal processing of food, a loss of up to 90% of vitamin B is possible, which is part of the raw products. For example, with frying meat, up to 95% of vitamin B 9 is destroyed, during cooking meat and vegetable products - from 70 to 90%, during the cooking eggs - about half.The deficiency of vitamin B 9 may develop due to its low content in the diet, the absorption of micronutrients in the intestine, or with an increase in the need for this substance (pregnancy, lactation period).
The common cause of this hypovitaminosis is the regular use of alcoholic beverages.
The lack of folic acid is the most common symptom in pregnant women and children of the first year of life. The deficiency of vitamin B 9 in the fetus is developing as a result of its lack in the body of the mother, and in infants - due to insufficient maintenance in breast milk.
Folic acid deficiency in a pregnant woman's body can serve as a factor in the whole a number of serious disorders:
- unbearable of the fetus;
- congenital malformations;
- mental retardation;
- pulk development of the nervous tube;
- spinal cleavage (in the fetus);
- the defects of the circulatory system;
- hunger lip or wolf mouth;
- anemia.
The lack of vitamin B 9 is not always accompanied by obvious symptoms. At the same time, according to the results of studies, a lack of folic acid is present in 20-100% of people, depending on the place of residence. This is one of the most common hypovitaminosis. However, even in the lack of certain clinical symptoms, the likelihood of a heart attack and stroke increases significantly, immunity falls.
Folic acid deficiency often leads to the development of pernicious anemia in premature children. The increase in vitamin needs in 9 occurs under a number of pathologies: leukemia, hemolytic anemia, chronic infectious diseases, carcassomatosis.
First of all, with a lack of vitamin in 9, Megaloblastic anemia is developing. At the same time, the Type of Malokrovia not only falls the content of erythrocytes in the blood, but also their activities are disturbed, since most of them do not ripen in the bone marrow. If not to fill the lack of folic acid, such symptoms are developing as a decrease in appetite, nervousness, decay of forces. Later vomiting, diarrhea, alopecia joined. Morphological skin impairment is possible, the appearance of ulcers in oral cavity and sip. If you do not proceed to treatment in time, megaloblastic anemia can lead to death.
In recent years, a number of clinical trials have been conducted, as a result of which it was established that vitamin C lacquer in 9, disturbing the metabolism of sulfur amino acids, leads to a delay in the blood of homocysteine \u200b\u200bamino acids. Homocysteine \u200b\u200bhas a negative impact on the intimidation of the vessels, which leads to the appearance of atherosclerotic plaques and increases the risk of heart attacks and strokes.
Vitamin B 9 absorption violation may occur during stomach diseases, gastronectomy when the body is lacking for anti-anemic factors (Castle factors) synthesized in the stomach. Folic acid can only be bored with anti-diamemine factors, respectively, with their deficiency, the level of folic acid in the blood drops.
In addition to folic acid, the Castle factor carries the cyanocobalamine into the blood. Therefore, the long reception of vitamin preparations in 9 in an increased dosage can lead to a lack of cyanocobalamin.
Also lack of vitamin B 9 is observed with heavy liver pathologies. It is in the liver that vitamin is transformed into tetrahydrofolate, which takes part in biochemical reactions. Folic acid in primary form is useless for the body.
If the body is experiencing a vitamin 9 deficiency, the work of the hematopoede system can be disturbed: the erythrocytes are dissolved, and defective cells are discarded into the blood, which are not capable of transporting oxygen. This is one of the reasons for the malformation of the nervous system in the fetus, since neurons cannot fully grow and develop under hypoxia.
Together with erythrocytes, the synthesis of leukocytes and platelets is disturbed, which can provoke a decrease in immunity and disrupt blood intake. In pregnant women, vitamin C 9 may be accompanied by iron deficiency. It increases the risk for both the mother and for the child.
Vitamin C 9 may develop with a lack of vitamins in the diet, starvation, compliance with unbalanced diets for weight loss. However, the most common factor in the lack of vitamin C 9 is dysbacteriosis. Dysbacteriosis develops as a result of prolonged, often uncontrolled reception of antibiotic drugs, incl. No appointment of a doctor.
In the United States, the law applies, according to which the manufacturer is obliged to add a certain amount of vitamin B 9 into the flour, in order to prevent the lack of this substance in consumers. In the US, the preventive dose of vitamin 9 is two times higher than in the Russian Federation.
Folee products containing folic acid
Vitamin B 9 is part of all tissues of man, animals, plants and microorganisms. The human body is not capable of producing folic acid. Therefore, it turns out from food, or is made by the microflora of the colon. Therefore, when violating the intestinal functions or dysbacteriosis, the production of vitamin B 9 may be insufficient. Such situations require an additional source of this micronutrient.Vitamin B 9 is contained in large quantities in vegetable food: spinach, onions, dill, parsley, beans, peas, buckwheat, oats, bran, bananas, walnut, grapefruit, drier, melon, yeast, pumpkin, mushrooms, beets, turnip and Dr.
Also, the source of folic acid is meat and products of animal origin: beef, lamb, pork, liver, kidneys, birds, milk, eggs, trout, perch, cheese, etc.
A plate of cereal porridge with milk and a glass of orange Fresh fill 50% of the daily need of the body in vitamin in 9.
The use of bifidobacteria stimulates the endogenous formation of folic acid in the intestine.
Vitamin B 9 quite quickly disintegrates under the influence of sunlight and simply with long-term storage of food, as well as in the temperature processing of products. Foliatic acid contained in vegetable food is destroyed faster. Folic acid in meat is more stable.
Therefore, to preserve vitamin in products, it is recommended to consume raw products. Vegetables are best consumed in the form of raw salads. In such a salad, it is best to add a garden cabbage, parsley, dill, beet leaves, mint or dandelion. It is also useful to add young nettle to salad. It is better to drink orange and tomato from juice - they contain the most folic acid.
Among meat products, the most folic acid is contained in the liver. The liver can be slightly frying and notably cook - with the vitamin B 9, which is part of its composition, is not destroyed.
Drugs containing folic acid
Tablets of folic acid - The most convenient dosage form for dosing (one tablet contains 1 mg of substance). In addition, today it is the most economical option. To fully fill the shortage of a pregnant woman in vitamin 9, it is enough to use 1 tablet per day. However, given the prevalence of folic acid deficiency, which may not appear externally, 2-3 months before pregnancy and in the first trimester you can take 2-3 tablets per day. Such a dosage is recommended by doctors, since an overdose from such a quantity is impossible, and the consequences of the lack of folic acid are extremely dangerous. In this situation, doctors resort to justified reinsurance.Folic acid is produced in the form of a drug Flavin. In one tablet of the drug contains 5 mg of vitamin B 9. It is much more daily norm even for a pregnant woman. Excess folic acid does not have a positive or negative effect, but simply excreted from the body. 1 Tablet Apot folika It also contains 5 mg of vitamin B 9. Considering the increased maintenance of the substance in the tablet, folacine and the apo folik apply only with acute and heavy vitamin deficiency. In order to prevent these drugs are not recommended.
In one tablet drug Folio Contains 0.4 mg of vitamin in 9 and 0.2 mg of iodine. The advantage of this dosage form is that it contains two micronutrients, so there is no need for an additional use of iodine preparations. The dose of vitamin B 9 in one tablet is low, so it is recommended as a preventive preparation. Folio is not appointed with an acute deficit or with an increased need for folic acid.
Vitamin B 9 is part of the polyvitamin preparations for pregnant women. Folic acid content in one tablet Each drug is different:
- Mantna - 1 mg;
- Elevit - 1 mg;
- Vitrum Prenatal - 0.8 mg
- Vitrum Prenatal Forte - 0.8 mg
- Multi-Tab Perinal - 0.4 mg
- Progranvit - 0.75 mg.
Vitamin B 9 is absorbed significantly better from drugs than from food.
In addition to pharmaceutical preparations, folic acid can be obtained from biologically active additives.
Indications
Folic acid is shown in the following states:- foliudiform anemia;
- anemia as a complication after gastroectomy;
- sPRA (tropical diarrhea);
- chronic intestinal inflammation;
- intestinal tuberculosis;
- pregnancy;
- lactation period;
- vitamin deficiency in 9.
- if pronounced signs of folic acid deficiency are observed (in this case, the dosage is calculated by the attending physician individually);
- if there are factors that increase the need for vitamin B 9, or stimulating its removal from the body.
- consumption of combined oral contraceptives before conception;
- consumption of maalox or phosphhalugel;
- acceptance of anticonvulsants during the planning period and during pregnancy;
- protein diet before conception;
- lack of plant food in nutrition;
- violation of the digestive tract;
- vomiting during pregnancy.
Clinical trials demonstrated that Vitamin B 9 can have a positive effect in the prevention of Alzheimer's disease. In persons with this pathology, as a rule, the content of folic acid and cyanocobalamin is reduced.
Method of application and dose
If a woman has any of the above factors, then during pregnancy planning and in the first trimester, it is necessary to consume 2-3 mg of vitamin at 9 per day. Also, the reception of the drug in increased dosage is necessary at a high probability of violation of the development of the nervous tube. Such a risk is present in women with epilepsy, diabetes, as well as in the presence of such violations in relatives in a straight line.The need for folic acid during pregnancy - 0.4 - 0.8 mg per day. However, with a deficient state, the dosage increases significantly in order to compensate for the lack of vitamin. The neural tube of the embryo begins to develop on the 3-5 week of pregnancy. At this time, a woman may not know about pregnancy, and not to pass a timely rate for compensation for folic acid deficiency. Therefore, Vitamin B 9 must be taken 1-3 months to the expected pregnancy. It is most important to maintain the necessary level of folic acid in the first trimester.
Folic acid must be taken during lactation in an amount of 0.3 mg per day (it is possible in the form of a multivitamin complex). This serves as a prophylactic course for both mom and baby. If you use a drug in elevated doses (for example, 1 mg), then the extra vitamin amount is simply excreted from the body of a woman, without harming neither to her nor the baby.
It is important to comply with the regularity in the use of vitamin B 9. However, given the fact that in any drug contains a dose that exceeds the daily need in vitamin, the pass of one reception should not cause anxiety.
- Atherosclerosis. 5 mg of vitamin at 9 per day for two weeks, then 1 mg. It is recommended to use in the form of a vitamin complex of the B-Group.
- Aphtose stomatitis. As a rule, AFTs (ulcers on the mucous membrane) appear together with cracks on the lips with a shortage of vitamins and micronutrients participating in hemopoiessee. Among them: Vitamin B 9, iron and cyanocobalamin. The recommended dosage is 5 mg of vitamin 9 3 times a day and 10 mg of iron glycinat for 120-180 days. Once in 30 days to make injections of cyanocobalamin - 1 mg. In the course of treatment, it is necessary to regularly check the level of cyanocobalamin.
- Viral hepatitis. Folic acid is used as auxiliary. It is recommended to take 5 mg 3 times a day for 10 days, then 5 mg times per day.
- Gingivitis and periodontitis. Take orally 1 mg of vitamin 9 times a day, make rinsing the oral cavity 2 times a day for one minute with 1% vitamin solution for 60-70 days.
- Depression. It is often observed in individuals with a deficiency of folic acid. Admission of 2-5 mg every day in a complex with vitamins B-Group.
- Osteochondrosis. Vitamin B 9 is involved in the formation of a frame of a frame, which accumulates calcium salts. Without a collagen frame, the bone does not acquire the necessary strength. Recommended dosage - once a day of 5 mg of vitamin B 9, 50 mg of vitamin B6, 50 mg of vitamins in the complex.
- Tough intestinal tumor. If any of your relatives in a straight line sought this oncological disease, it is strongly recommended to take 1-5 mg of vitamin in 9 and 100 mg of vitamins in the complex.
- Spasm colon. It is manifested in the form of alternating conservation and diarrhea, colic and bloating. The lack of vitamin B 9 may lead to a chronic confusion, which leads to a colon spasm. It is necessary to start with 10 mg of vitamin once a day. If 15-20 days of progress is not observed, it is necessary to increase the dose to 20-60 mg per day before the occurrence of a positive effect. Next, the dosage is gradually reduced. At the same time, it is recommended to take 1 time per day at 0.1 g of vitamins in the complex. During the course, it is necessary to regularly check the level of cyanocobalamin. In the diet, it is recommended to include oat bran containing water-soluble fiber. Wheat bran in this case are not suitable, since their fiber is insoluble.
- Epilepsy. After an attack of epilepsy, the level of vitamin B 9 in the brain is reduced. Anticonvulsants also reduce its blood plasma concentration. As a result, attacks are rapidly. Usually, when epilepsy is assigned 5 mg times per day. However, take the drug only after consulting with the doctor.
Overdose
Overdose happens very rarely. For this, the body should receive hundreds of times larger than the required amount of folic acid (20-30 mg). With a minor exceeding the required amount of the drug, excess of folic acid is derived, without having no harm to the body. At the same time, as any medication, vitamin C 9 can cause allergies.A serious minus of prolonged reception of vitamin C drugs is that it hides the symptoms of megaloblastic anemia, but does not stop neurological disorders characteristic of this disease. Therefore, with prolonged reception of vitamin drugs in 9, a hidden progression of heavy neurological disorders due to the lack of cyanocobalamin is possible. Just 10 years ago it was considered that the overdose of this micronutrient does not happen. However, studies are now known, which indicate that pregnant women who have long used vitamin preparations in increased dosage, children with a weak immunity, a tendency to bronchial asthma and colds, are born.
Hypervitaminosis
Increased doses of vitamin B 9 can provoke dyspepsia from a child or increased excitability. Prolonged use of vitamin in increased dosage is not recommended, as this may lead to a drop in the blood content of cyanocobalamin.Side effects
Depending on individual tolerability, folic acid preparations can cause allergic manifestations, bronchial spasm, leather redness, hyperthermia, rash.Vitamin B 9 does not have toxic impact on the human body. Clinical studies were conducted on long-term use of vitamin B 9 in a dosage of 15 mg per day (40 times higher than the daily need of the body). According to the results of studies, the drug did not have any toxic effect. However, prolonged reception (more than 90 days) Vitamin B 9 in increased dosage can lead to a drop in the level of cyanocobalamin in the blood, which can provoke anemia. Increased doses of vitamin can provoke disorders of the digestive tract, increase excitability, cause imbalance in the work of the kidneys.
Some drugs reduce the content of vitamin 9 in the blood plasma. Among them:
- acetylsalicylic acid (in high dosage);
- nitrofurans (taken with urinary tract infections);
- combined oral contraceptives;
Folic acid and male health
Vitamin B 9 is necessary for both women and men. In the chronic shortage of vitamin, men can develop a number of pathologies, including infertility and megaloblastic anemia. The technique of folic acid in the therapeutic dosage excludes such complications.The main indicator male health It is considered to read the state of sperm. Sperm - these are the same cells, protein and nucleic acids are needed for their synthesis. In the absence of vitamin in 9, the synthesis of spermatozoa is broken. With a lack of vitamin, the concentration of spermatozoa decreases, and their condition deteriorates: spermatozoa can have an unnatural shape or not to have a tail, which reduces their mobility. But the worst thing is that in such spermatozoids there may be an irregular number of chromosomes, and this is the main factor in hereditary diseases in children (for example. Down syndrome).
Vitamin B 9 and Hormone Testosterone causes the normal development of spermatozoa. Folic acid is extremely important for men in the pubertal period, since it is one of the factors for the development of secondary sexual signs (voices flaking, vegetation on face and body, intense growth).
Folic acid in the treatment and prevention of oncological diseases
Vitamin B 9 warns oncological diseases. But if the disease has already begun, it is impossible to use the drug, since folic acid will contribute to division and cancer cells. In such situations, medicines are used, which inhibit vitamin C 9, for example, methotrexate. It slows down the magnification of the tumor. In order to prevent the metabolic disorders, a drug is prescribed, replacing vitamin B 9 - folinic acid. Given the higher risk of cancer in the elderly, it is not recommended to use folic acid preparations without the recommendation of the doctor.Lovekovorin - a medicinal product based on folinic acid, successfully used in chemotherapy oncological diseases. It reduces the severity of intoxication after the use of cytostatic drugs (vomiting, diarrhea, hyperthermia, bone marking tissue damage).
Recent studies of scientists in the United States have proven the relationship between the admission of vitamin drugs in 9 and the progression of the tumors of the large intestine.
Since 1980, at Harvard, a survey was organized every 2 years, in which approximately 90,000 women with children participated. Questions related to nutrition and, individually, receiving vitamin complexes. In 1994, the collected information was carefully studied for the incidence of a thick bowel cancer - a third-party cancer among women in the United States. Polls these have shown that women who took a sufficient amount of vitamin 9 are more than 0.4 g mg per day, less often suffered from this disease.
Scientists concluded: 75% of cases of the tumor of the large intestine in women can be avoided if we use preventive doses of vitamin in 9 during the lifetime.
Studies allowed to take another important conclusion. Less frequently, the Tolstoy Intestinal Tumor met in women, who for the last 10-15 years regularly used the vitamin complexes.
Folic acid and prevention of atherosclerosis
Recently, doctors are increasingly inclined to the belonging that folic acid is effective in the prevention of atherosclerosis - the main factor of the disease of the cardiovascular system.Today in the West countries, the new theory of pathogenesis of atherosclerosis is popular. According to this theory, the main reason for the progression of atherosclerosis is the high level of blood not to all known cholesterol, and the other bioactive factor is homocysteine.
Homocysteine \u200b\u200bis an endogenous amino acid. Under the influence of enzymes in the body, it is transformed into an indispensable fatty amino acid methionine involved in the production of protein. If the body is lacking for the corresponding enzymes, homocysteine \u200b\u200baccumulates in the blood and destroys the walls of blood vessels, causing inflammation. Cholesterol participates in this process at later stages. Supporters of the new theory argue that without homocysteine, even at an elevated level of cholesterol in the blood, atherosclerosis does not progress.
What is the role of folic acid in this key? The fact is that it is it necessary for the synthesis in the organism of enzymes transforming homocysteine \u200b\u200bto methionine. The deficiency of vitamin B 9 causes a deficit of the corresponding enzyme. As a result, extra homocysteine \u200b\u200bis accumulated in the blood, which leads to the progression of atherosclerosis, and then to its complications - the ischemia of the heart muscle, infarction, stroke.
Before use, you must consult with a specialist.Women who plan to get pregnant should be carefully and consciously prepare for this period: lead healthy image Life, delight yourself, do not be upset by trifles. In addition, you need to start taking special drugs. One of these is folic acid for pregnant women.
When the reception of folic acid is shown during pregnancy
Folic acid or vitamin B9 is given an important role in the formation of new blood cells. The lack of such a substance often leads to anemia, and the use of the drug is important for replication, cell growth, antimicrobial therapy. Often at the reception of the gynecologist when the substance is assigned, women are interested, why drink folic acid during pregnancy? According to experts, B9 is needed by each pregnant, because It is able to prevent some defects in the development of the CNS Baby.
It is advisable to start using the drug still during pregnancy planning, because all processes involving the drug that occur in the formation of the fetus proceeds in a small period - that is, when future mom Do not even know about the child. It is necessary that folic acid during pregnancy entered the female organism at the first weeks, since this period is the main thing in the formation of the neural tube embryo.
What is useful for folic acid pregnant
Vitamin B9 stimulates the formation of nucleic acids, which are the basis of all cells in the body. The drug is necessary for all rapidly divided tissues in humans. Moreover, useful properties Substances are what it is:
- stimulates blood formation;
- blocks the formation of cancer cells;
- restores muscles during pregnancy;
- participates in the creation of the placenta;
- promotes the normal operation of the digestive tract;
- participates in metabolism.
How to drink folic acid during pregnancy
Preferably vitamin B9 to use all future mothers for preventing anemia (up to 12 weeks). The decision on how to make folic acid during pregnancy, approves only a gynecologist. In our country, there is a norm for women awaiting a child, 1000 μg is one tablet, but high doses can be appointed to some moments on the results of analyzes. This applies to patients who, during the examination, detected defects in the development of the fetus were discovered.
In tablets
A popular drug with a small price - folic acid for future mothers satisfies all the needs of vitamins. It is only a doctor: based on the characteristics of pregnancy, it is necessary to drink 1-3 tablets one or three times a day. For the prevention of the disease, only one capsule 1 mg is taken, the dosage of the drug in women with a vitamin deficiency is greatly increased - up to 5 mg.
Vitamin B9 is almost all polyvitamins, which appoints a gynecologist during pregnancy. When taking such complexes there is no need to separately use folic acid if there is no indication to this. One of the most popular drugs for future mothers is considered to be Folio - this complex contains vitamin B9 (400 mg) and iodine (200 mg). You need to take on one tablet per day. Polyvitamins in which there is vitamin B9:
- Multitabs-prenatal contains 400 mg of substance;
- in Materna and Elevote, 1 mg of substance is located;
- the composition of the pregnavitus will provide a substance of 750 μg;
- in Vitruum, there are 800 mg of vitamin.
Vegetarians, as a rule, are not familiar with the deficit of vitamin B9, because It is contained in the leaves and vegetables of green. Another people with insufficient receipt of plant food (especially in winter) should be additionally added to the vitamin complex. Important item is contained in:
- green leaves of spinach, salad, bow, asparagus, parsley, cabbage;
- green peas;
- avocado;
- cheese, kefir;
- citrus;
- baking cooked from coarse flour;
- pumpkin;
- icra;
- fruit: apricots, melons, peaches;
- sunflower seeds;
- bobah;
- yeast;
- egg yolk;
- walnuts;
- dry milk, cottage cheese;
- beef liver.
How many folic acid need to drink pregnant
For a normal functioning, an adult man should drink 0.2 mg vitamin B9, but when you enter the baby, the need for substance increases. The daily dose of folic acid for pregnant women is 1000 μg - this is one tablet. Many women are embarrassing such numbers, but it is not worth worrying. The overabundance of the substance comes only when a person drinks 25 tablets at a time. In other cases, excess vitamin is derived without much consequences.
With health problems (diabetes, intestinal diseases, epilepsy) and a pronounced disadvantage of a woman, a doctor can prescribe strong drugs that contain vitamin B9: APO-Folic (price 200 rubles) or FOLASIN (price 125 rub.). In one tablet, such funds contain 5 mg of folacine, and this is already considered a healing dose.
Folic acid rate during pregnancy in 1 trimester
The first months of embryo tool - the most an important periodbecause It depends on the further pregnancy, formation and development of the fetus. In 1 trimester, you should make sure that the female organism gets the required amount of all minerals and vitamins. This is especially true of folic acid, which at an early stage can prevent the development of damage to the nervous system of the kid. Only a small part of substances can be assisted with products, so it is necessary to take medical medications with vitamin B9.
When entering the baby, the daily dose of the drug may be different, in the first 3 months it is necessary to consume 2 times a day at 0.4 mg. Often the substance is part of the complexes, but it is better to take it separately. Drinking tablets should be at one time and preferably before meals. It is necessary to drink them with clean ordinary water. It is not recommended to use coffee, tea or packaged juices.
To what period of pregnancy take
With a drug that contains a useful element, future mothers introduce the first consultation. Many doctors believe that as a separate means it is necessary to take only the first 3 months, then it should be switched to a vitamin complex for pregnant women. Although there are such specialists who claim that B9 is needed by the feminine body all life, and during pregnancy should not stop his reception after 12 weeks. In any case, the dosage and time of application should only gynecologist.
Side Effects of Folic Acid
For a person, Vitamin B9 is completely non-toxic, the drug practically does not give side effects. The overdose of medication during pregnancy may occur only in case of exceeding the daily dose 100 times. Rarely the drug causes allergies that may appear due to the individual intolerance to the substance. Long taking high doses can adversely affect the health of women and baby. The following side effects arise at the instructions for the medicine that at a large concentration of it in the body.
- the content of cyanocobalamin is reduced in the blood, which can provoke anemia of pregnant;
- changes in the work of the kidneys;
- hyperoportability;
- pCT disorder.
Price folic acid during pregnancy
Preparations with vitamin B9 are sold in tablets without a recipe on any pharmacy. The average price for the medicine is from 30 to 80 rubles. You can purchase folic acid inexpensively in large supermarkets where there is a pharmacy point, and in addition, vitamin can be bought and order in an online pharmacy. In this case, the cost of the fund will depend on the company of the country of the manufacturer and form of release.
Folic acid is one of the most common substances that are prescribed to future mothers. This acid will become excellent assistant When planning pregnancy. It participates in many fundamental fetal development processes. The body does not produce it, so when planning and occurring pregnancy, the doctor prescribes its use.
What is folic acid?
Folic acid is a special vitamin B, designed to activate many processes in the human body. It is not synthesized in blood independently. His drawback is observed in the body of almost every second woman. The substance is contained in some products, but it is impossible to say with confidence that people are guaranteed daily take them in sufficient quantities.
Otherwise, psycho-emotional instability may be observed, reduced performance and even the development of many serious ailments, such as Malokrovia. It is necessary to fight these challenges. It is necessary from the first week of pregnancy to take this substance. It is advisable to start at the planning stage.
When do the drug prescribe?
Many people do not know about the benefits of medication and do not understand why doctors prescribe it so often. Folic acid is recommended for all pregnant women in the first, second and third trimesters, as well as those who else only plans to have a child. This indispensable substance and its sufficient amount in the body is a determining factor in the process of forming the nervous tube of the fetus.
In addition, its benefits are noted for the proper functioning of the placenta. Women who long take folic acid reduce the risk of premature births or miscarriage. Vitamin B9 is involved in the formation of white blood cells, contributes to the normal absorption of iron.
The lack of folic acid provokes the development of the following diseases from the future kid:
- hydrocephalus;
- muscle delay and brain development;
- other pathologies and defects.
What is the daily dose?
Folic acid content in the body healthy man Makes up 200 micrograms. However, a woman should provide a doubled agent substance for a period of pregnancy. Both when planning and while waiting for the future kid, the dosage of folic acid should be from 0.8-0.9 mg to 3.5-4 mg per day. In the early stages, its number is less than in later. A specific number appoints a doctor. It is necessary to avoid dosage, because it hurts the body of a woman and the fetus.
Instructions for use and dosage
Folic acid is convenient for use, since its use does not depend on food intake. It is necessary to put the drug at the appropriate time with an abundant amount of non-carbonated water. If you need to use 2-3 times a day, it is better to choose for this one and the same hour every day. The drug is appointed at the stage of the child planning. Many are thinking to what week of pregnancy to take folic acid. As a rule, a woman does not stop using vitamins even after the birth of the baby.
When planning
Folic acid benefits if you start using it 1-2 months before pregnancy. It is useful for both future parents.
If the pregnancy was unplanned, you need to start the reception from the first weeks. The dosage is appointed taking into account the individual characteristics of the human body. Detailed advice must be obtained from a specialist.
1 trimester
As a rule, 1 trimester involves a two-time adoption of the drug in the dosage of 400 μg in the morning and in the evening. It is best to choose the same time for this daily. This is especially important at the beginning of pregnancy, since during this period all the most important processes are held. It is not recommended to drink the drug with juices, tea, coffee. Normal non-carbonated water is suitable.
2 trimester
With the development of the embryo, doctors recommend increasing the dosage of vitamin B9. In 2 trimester, it should increase to 600 μg per day. This will allow you to maintain good mothers well-being and prepare an organism for upcoming birth. It is important not to throw the reception and clearly follow the instructions and prescriptions of the doctors.
3 trimester
Despite the fact that 3 trimester is more comparative stability, it is necessary to continue to strengthen their own health and drink vitamins. At this stage, the daily dose of folic acid increases to 800 μg.
The required amount of the drug is a purely individual indicator. The doctor when discracing the recipe is based on the results ultrasound Research and analyzes. If there is an increased risk of developing defects and pathologies of the fetus, the dose will be somewhat larger.
What threatens the overabundance of folic acid in the body?
Despite the fact that Vitamin B9 is a necessary substance for the body of each person, especially a pregnant woman, you need to approach his reception with great attention and care. Overdose of folic acid can provoke unpleasant symptoms and diseases. Among the most common:
- bitterness in the oral cavity;
- sharp decline in appetite;
- discomfort in the branch bodies: bloating, diarrhea;
- unreasonable anxiety, anxiety;
- unstable psycho-emotional state;
- restless sleep or insomnia;
- provocation of the deficiency of vitamin B12 in the blood.
Overdose of the drug during pregnancy is rare. Folic acid The body absorbs in the required quantity. It is partially removed by the liver, the rest of the body goes through the kidneys. In almost 100% of cases, the reception of folic acid is not accompanied by any side effects.
Contraindications and side effects
The big advantage is that folic acid is not toxic at all, so it is extremely rarely rarely side effects. However, before starting to drink it, it is necessary to consult with a competent specialist. He will explain how many times a day and in what quantity to take pills according to the individual characteristics of the body and the results of the analyzes.
Before starting the reception, it is necessary to familiarize yourself with contraindications that have folic acid. The drug is not recommended to people who have diagnosed the following diseases:
- chronic pyelonephritis;
- bronchial asthma;
- pernicious anemia.
The reception must be eliminated by those whose coming relatives had malignant education. It is recommended to exclude folic acid to people with vitamin B12 deficiency. Natural contraindication is allergic to this drug.
Specialists note the absolute non-toxicity of folic acid and the safety of its use. Hence the low percentage of side effects. There is a small probability of appearance. allergic reactionswhich provokes the individual intolerance to the substance.
Side effects may occur only if you systematically exceed the recommended dose of tablets. These include 5 main problems:
- hyperoportability;
- insomnia;
- disorder of the gastrointestinal bodies;
- changes in the functioning of the kidneys;
- reducing the content of cyanocobalamin in the blood of a pregnant woman, which can later cause anemia.
Which products have folic acid?
Folic acid The human body can receive and naturally, without taking tablets. Especially a lot of vitamin B9 in fruits and vegetables. If it is necessary to increase its content in the body, it is necessary to increase the consumption of cucumbers, carrots, bananas, oranges and apricots. Beets and bean crops are useful. Champs should be taken from black currant leaves, nettle, mint and dandelions.
A large amount of folic acid contains nuts - up to 240 μg of the useful substance. Folic acid is rich in the gifts of the forest - mushrooms and berries. The most popular among them is raspberry. It contains a large amount of vitamins, among which it includes B9.
The above products can be used in raw form, but it is better to prepare a full-fledged dish of them. So that they do not lose their properties, you need to expose them minimal heat treatment.
Folic acid preparations
Folic acid is contained in the drug folio. It includes vitamin B9 and iodine - in one medicine, two useful elements are combined. The drug helps to minimize the likelihood of pathologies and defects of the internal bodies of the baby.
Folic acid and iodine - indispensable substances for each person. Many doctors talk about what benefit is contained in the folio, and recommend applying it systematically. Vitamin B9 provides the possibility of normal fetus development, and iodine provides a stable state of health and well-being of all pregnancy. This is exactly what the future mother awaits. How much does folio cost, you can learn in pharmacies catalogs.
Another means that contains this acid is Foliber. It is relatively safe, rarely causes side effects, but you can take an appointment of a doctor. When unwanted reactions are observed, it is necessary to refuse.
Prices for drugs vary depending on the region. To what period of pregnancy take folic acid? It should be borne in mind that the drug will be needed after the birth of a child. When follows all the instructions and instructions of doctors pregnancy will pass Easy, and the baby will be on the light of healthy.